Saturday, January 21, 2012

Romney offshore accounts contain up to $32 million (AP)

WASHINGTON ? Republican presidential candidate Mitt Romney owns investments worth between $7 million and $32 million in offshore-based holdings, which are often used legitimately by private equity firms to attract foreign investors. Such offshore accounts also can enable wealthy investors to defer paying U.S. taxes on some assets, according to tax experts.

An Associated Press examination of Romney's financial records identified at least six funds set up in the Cayman Islands, a small Caribbean island chain that has long been used as a base for international investments because of low tax rates and financial secrecy. Romney has acknowledged that some of his investments are based in the Caymans, but he has not identified all of the specific accounts and the amounts based there. There is no indication Romney uses the accounts to dodge any U.S. tax obligations.

The Caymans have often been associated with individuals and corporations seeking to avoid paying U.S. taxes. However, it is legal for U.S. residents to own investment accounts that are set up there ? if they file the proper forms with the Internal Revenue Service and pay the appropriate taxes.

"If you file the forms and report the income, you are 100 percent legal," said Kevin Packman, a Miami lawyer who chairs the offshore tax compliance team at the law firm of Holland & Knight.

Independent tax policy experts said Romney's use of the Cayman-based investments was legal, but some criticized the strategy as a province of wealthy investors allowed by a tax code studded with loopholes.

"The bottom line is, they're taking advantage of a system that's flawed," said Nicole Tichon, director of Tax Justice Network USA, part of a global network promoting tax transparency. "It may be legal, but these are loopholes that show problems in our tax code."

The six Romney offshore holdings are in investment funds run by Bain Capital, the private equity powerhouse he led in the 1980s and 1990s. The six funds are listed only by name and a range of amounts in Romney's financial records, but the Cayman addresses are in other corporate documents filed with the U.S. Securities and Exchange Commission and in foreign investment portfolios.

Five of the Cayman-based funds are included within a blind trust for Romney's wife, Ann, and worth between $2.8 million and $7.6 million.

A sixth fund, called Bain Capital Investment Partners Trust Associates lll, is part of Romney's IRA retirement account and worth between $5 million and $25 million.

In a financial report last August, Romney declared a family fortune worth as much as $250 million. The six Cayman funds are among dozens of investments the Romneys have owned since he left Bain in 1999 to organize the 2002 Olympic Games in Salt Lake City and then pursue a career in politics.

A Romney spokeswoman, Andrea Saul, said the Cayman funds "are taxed in the very same way they would be if those funds were established in the United States." She noted that because many of the funds are in a trust directed by a Boston lawyer, the Romneys played no role in deciding how the money was invested.

Saul said the decision to set up the funds in the Caymans was made by the funds' sponsors ? in this case, senior partners at Bain Capital, not Romney. A Bain spokesman declined to comment on the funds' origins.

Tax experts and lawyers said using offshore funds to attract foreign investors is a legitimate and standard business practice. Increased foreign investment in a U.S. fund based abroad could increase financial returns for American investors. Offshore funds offer advantages for U.S. investors looking to diversify their portfolios and for foreign investors seeking to avoid U.S. reporting and tax-withholding requirements.

"If you have a foreign investor who is making income largely abroad and doesn't want to be subject to U.S. regulations and reporting, it's a plus," said C. Eugene Steuerle, co-founder of the Urban-Brookings Tax Policy Center and former deputy assistant treasury secretary for tax analysis.

Under American law, U.S. investors must pay taxes on profits made from offshore investment funds. However, U.S. investors may be able to defer those taxes until later as they bring the profits into the U.S., depending on how the fund is structured, said Kevin Packman, chairman of his firm's offshore compliance team at Holland & Knight of Miami.

Some hedge fund and private equity managers route IRA retirement holdings through an offshore entity set up as a "blocker corporation," an affiliate of a private equity fund that acts as a way-station, storing the retirement funds while investing an identical amount in the actual fund. This complicated maneuver allows the investor to defer paying a 35 percent tax on earnings that the IRS considers "unrelated business income," said Michael J. Graetz, a Columbia University law professor and an authority on national and international tax law.

The 35 percent tax is aimed at pension funds, university endowments, hospitals and other nonprofit organizations when they invest in private equity funds that borrow large amounts of money to buy other companies. But nonprofits can use the offshore blocker funds to defer those tax payments, and similarly, IRA accounts can be routed through blocker accounts, depending on how tax plans are structured, Graetz said.

"One of the major functions of tax planning is to defer payments and deal with them down the road instead of today," Graetz said. "For an IRA account, it's not so much a tax rate game as it is a timing game."

Romney's other offshore-based investments would not benefit from that structure, Graetz said. But their earnings could be boosted by blocker corporations that promote investments by nonprofits, he said.

Romney's taxpaying strategy may become clearer when he makes his 2012 tax returns available in April as he has promised.

Congress has tried to make it harder for investors to defer tax payments by broadening requirements that U.S. investors in foreign-based funds pay taxes as they earn profits. But aggressive tax planners can still find ways to get around the rules, experts said.

"You have to look at each investment and its structure before you can pass judgment," Steuerle said.

Benefits to deferring tax payments include the ability to reinvest the deferred taxes, earning higher returns before bringing the money into the U.S. A wealthy investor who has no immediate need for the money would be able to keep the investment offshore indefinitely, never paying U.S. taxes on it.

Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/ap/20120120/ap_on_el_pr/us_romney_offshore

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African Union troops reach outskirts of Mogadishu

In this photo taken Thursday, Jan. 19, 2012, a displaced Somali woman walks past an armored vehicle of the African Union (AU) peacekeeping force that was transporting journalists in Mogadishu, Somalia. Heavy fighting broke out in Somalia's capital on Friday as the African Union peacekeeping force encountered resistance as it pushed to Mogadishu's outskirts for the first time, the latest move in an offensive against Islamist insurgents. (AP Photo/Ben Curtis)

In this photo taken Thursday, Jan. 19, 2012, a displaced Somali woman walks past an armored vehicle of the African Union (AU) peacekeeping force that was transporting journalists in Mogadishu, Somalia. Heavy fighting broke out in Somalia's capital on Friday as the African Union peacekeeping force encountered resistance as it pushed to Mogadishu's outskirts for the first time, the latest move in an offensive against Islamist insurgents. (AP Photo/Ben Curtis)

In this photo taken Thursday, Jan. 19, 2012, a soldier from the African Union (AU) peacekeeping force mans the gun turret of an armored vehicle while transporting journalists in Mogadishu, Somalia. Heavy fighting broke out in Somalia's capital on Friday as the African Union peacekeeping force encountered resistance as it pushed to Mogadishu's outskirts for the first time, the latest move in an offensive against Islamist insurgents. (AP Photo/Ben Curtis)

In this photo taken Thursday, Jan. 19, 2012, a displaced Somali man pushes a wheelbarrow past an armored vehicle of the African Union (AU) peacekeeping force that was transporting journalists in Mogadishu, Somalia. Heavy fighting broke out in Somalia's capital on Friday as the African Union peacekeeping force encountered resistance as it pushed to Mogadishu's outskirts for the first time, the latest move in an offensive against Islamist insurgents. (AP Photo/Ben Curtis)

In this photo taken Thursday, Jan. 19, 2012, displaced Somali boys wave, seen through the plate glass window of an armored vehicle of the African Union (AU) peacekeeping force that was transporting journalists in Mogadishu, Somalia. Heavy fighting broke out in Somalia's capital on Friday as the African Union peacekeeping force encountered resistance as it pushed to Mogadishu's outskirts for the first time, the latest move in an offensive against Islamist insurgents. (AP Photo/Ben Curtis)

In this photo taken Thursday, Jan. 19, 2012, a displaced Somali boy gestures towards a soldier from the African Union (AU) peacekeeping force providing security for visiting journalists in Mogadishu, Somalia. Heavy fighting broke out in Somalia's capital on Friday as the African Union peacekeeping force encountered resistance as it pushed to Mogadishu's outskirts for the first time, the latest move in an offensive against Islamist insurgents. (AP Photo/Ben Curtis)

(AP) ? Heavy fighting broke out in Somalia's capital on Friday with African Union peacekeepers encountering resistance as they pushed to Mogadishu's outskirts for the first time, the latest move in an offensive against Islamist insurgents.

Hundreds of residents fled a northern Mogadishu neighborhood after waking to the sound of mortars and gunfire. AU troops have largely pushed al-Shabab militants out of the city over the last year, but pockets of resistance remain.

Resident Abdirahman Ahmed said he was awakened by "noisy mortars" on Friday, said that al-Shabab fighters appeared to be moving back into the northern neighborhood of Heliwa.

"We want to flee now," he said, adding: "People are nervous."

Lt. Col. Paddy Ankunda, the spokesman for the AU force that is known as AMISOM, said Friday was the first time that AU forces moved outside of Mogadishu.

"We are moving out of the city now so we can defend the city from outside now. Our troops have captured strategic bases from al-Shabab," Ankunda said.

The nearly 10,000-strong AU force was confined in previous years to small slices of Mogadishu, but the push to expand their zones of control over the last year have been largely successful. The AU force is working side by side with Somali troops, but most of the gains have been made by the better trained and equipped troops from Uganda and Burundi.

Al-Shabab is also being pressured by Kenyan military forces in Somalia's south and Ethiopian forces in the west.

East African nations want the U.N. Security Council to authorize an increase in the number of troops inside AMISOM to 17,000. Kenya has also asked the U.N. for its forces inside Somalia to be integrated into the AU.

Militants continue to carry out suicide and roadside bomb attacks in Mogadishu. At least six bombs were found or exploded in the capital since Wednesday, including a blast on Thursday that killed six people.

Meanwhile, the AU force commander, Maj. Gen. Fred Mugisha, said that around 3,000 Somali troops had not received their wages for the past four months. The AU is supposed to pay them with money donated by Italy, but Mugisha said the Italians had not yet sent the cash. The delay in payment had caused some soldiers to desert their posts, he said.

"It will have an impact on morale," he said.

Around 7,000 other Somali soldiers are paid by the U.S. through a separate program.

Somalia hasn't had a functioning government in more than 20 years. The current transitional government, whose mandate ends in August, is paralyzed by political infighting. The U.N. is pressing government leaders to resolve their differences and expand the areas in the country the government provides services to.

Somalia has also been dealing with a famine the last six months that is estimated to have killed between 50,000 and 100,000 people. Friday was the six-month mark since the U.N. declared famine in Somalia on July 20.

___

Associated Press reporter Katharine Houreld contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2012-01-20-AF-Somalia/id-77764a0695af4b9ca4a8fc057e789b03

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Friday, January 20, 2012

Tanier: Sunday's tight ends are future of NFL

Teams' tight ends impossible to defend due to their size, speed and versatility

Image: DavisGetty Images

49ers tight end Vernon Davis breaks a tackle by Saints defender Malcolm Jenkins.

ANALYSIS

updated 10:25 p.m. ET Jan. 17, 2012

Mike Tanier

Twenty-five years ago, tight ends were going extinct.

The run-?n?-shoot offense provided roster space for eight wide receivers and zero tight ends. The West Coast Offense offered a niche as a king-sized possession receiver, but as specialization and substitution increased, the tight end became a threatened species, if not an endangered one.

Gradually, tight ends evolved into the modern Tony Gonzalez-Jason Witten breed: beefed up slot receivers for whom blocking is a nights-and-weekends job. These latter-day of tight ends are often the best overall athletes on the field, but that makes sense -- when a species is pressured, only the fittest survive.

Tight ends are still evolving. Given how athletically gifted they are, it?s not surprising that the 49ers and Patriots are finding new roles for players like Vernon Davis, Delanie Walker, Aaron Hernandez, and Rob Gronkowski.

Just when you think the Patriots tight ends are old news, they turn into running backs. Just when you think you have Davis figured out (Greek statue come to life, though sometimes with the hands to match), he proves that he is as dangerous a deep threat as any of the wide receivers left in the playoffs.

If these guys represent the next stage -- Version 4.0 -- in the metamorphosis of the tight end, we should get a better handle on what they are doing. The Super Bowl could hinge on something as unlikely as the tight end around, a play a fan could go a decade without seeing before this season.

The running threat
Just how unusual is it for a tight end to take a handoff? The top five active reception leaders among tight ends ? Tony Gonzalez, Jason Witten, Antonio Gates, Jeremy Shockey, and Todd Heap -- have combined for 3,473 receptions but just 11 running plays. So rushing accounts for about 0.3 percent of a tight end?s production, though even that number is skewed by broken plays, fake punts, and other odds and ends that count as ?runs? in the official stats.

Greats like Witten, Gates, and Kellen Winslow the First went their whole careers without a carry.

It wasn?t always that way. The ?tight end around? was a playbook standard through the 1960s, and as recently as the late 1970s, a great tight end like Ozzie Newsome might take a few handoffs per season as a fullback or on a reverse. Tight end handoffs disappeared by the early 1980s, but the Patriots and Niners are at the forefront of a revolution in tight end running.

Jim Harbaugh is determined to revive the tight end around, no matter the costs. Davis and Walker combined for five carries this season, all of them outside runs. Some of those runs came at unusual times, like in the red zone and third-and-long. Most, however, were unsuccessful. Walker gained 14 yards on one end-around, but the other four plays lost yardage. Still, Harbaugh was calling Walker?s number as late as Week 14, and the man that gave us the Alex Smith shotgun sweep for a touchdown against the Saints will do anything to diversify his running game.

The Patriots don?t run many tight-end arounds. Instead, Hernandez lines up in the backfield and takes old-fashioned handoffs. Hernandez rushed six times for 45 yards in the regular season and added five rushes for 61 yards on Saturday against the Broncos. Gronkowski is also credited with a two-yard touchdown rush, but that was more of a short screen pass that happened to be travel backward in the air.

There is nothing new about lining tight ends up in the backfield on passing downs, but they are usually there for pass protection, not as rushing threats. For the Patriots, Hernandez?s rushing is just one more advantage for their no-huddle offense; even if the running backs are split wide or on the sideline, defenders cannot ignore the possibility of a handoff.

But really, no team needs an extra reason to get the ball into the hands of athletes like Davis, Walker, Hernandez and Gronkowski. They are almost as fast as wide receivers and bigger and stronger than most running backs. Tall ball carriers are at a disadvantage when running between the tackles because they expose the football (and the ribs) when plunging into the line. That is less of a problem on the edge, and when a 250-pounder like Hernandez reaches the sideline ? where only 190-pound cornerbacks are available to tackle him ? good things can happen for an offense.

The deep threat
Tight ends have always run deep routes; the ?seamer? is an important part of every playbook. The next-gen tight ends are going a step further. Instead of settling for a role as occasional deep threats, they are on their way to becoming their teams? primary deep threats.

Table 1 shows just how often the Patriots and Niners tight ends were targeted for deep passes (more than 15 yards downfield in the air).

PlayerAttCompYardsTDsAvg Yards in Air
Hernandez/Gronkowski3921501822.5
Davis/Walker2815374325.3
Pettigrew/Scheffler2415341320.1

Gronkowski and Hernandez are targeted about three times per game on deep passes. Davis and Welker are targeted less frequently, but the Niners do not pass nearly as often as the Patriots. As a percentage, their role in the long passing game is similar to the one Gronkowski and Hernandez play, and their ?long passes? are actually longer than the Patriots? bombs.

For comparison?s sake, I added Brandon Pettigrew and Tony Scheffler, another tight end tandem that plays a major role in the deep passing game. The Lions? duo is targeted nearly as often as the Davis and Walker, but again, the Lions pass much more often than the Niners do. Davis and Walker combined for 39.4 percent of the Niners' deep passing attempts. Scheffler and Pettigrew accounted for just 20 percent of the Lions' deep passing. Hernandez and Gronkowski account for 38 percent of the Patriots' deep passing.

Pettigrew and Scheffler are fine players, but they are Version 3.0 tight ends. Version 4.0 models are full partners in all facets of the passing attack.

The next step
The most interesting thing about the Patriots and Niners tight end tandems is that they are tandems: both teams make extensive use of two tight-end attacks. The Lions and Panthers are also committed to the two tight end package as one of their base offensive sets.

Sure, these tight ends motion into the slot, split wide, or line up at fullback. But they are recognizable as tight ends. If you told a coach from 1990 (when even the Redskins had given up their two tight-end formation for the three-receiver ?posse?) that some of the most successful, explosive offenses in the league would be built around tight end passing, he would have sent four 5-foot-9 Smurf receivers to chase you and hit you as hard as they could (not very).

The old, lumbering tight end is not quite extinct, as the Giants' Jake Ballard will prove on Sunday. But defenses must brace for a new breed of player that can not only work the slot and seam like Gonzo and Witten, but take handoffs, run the full route tree, and stay on the field on every situation. And block. Players like Walker have not forgotten that part of their job description.

So if you are watching a Saints game three years from now and see Jimmy Graham as a Wildcat quarterback, or if Jermichael Finley starts lining up in the I-formation for the Packers next year, remember how it all started.

It?s nothing to be afraid of. It?s evolution, baby.

Mike Tanier writes for NBCSports.com and Rotoworld.com and is a senior writer forFootball Outsiders.


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Source: http://nbcsports.msnbc.com/id/46027185/ns/sports-nfl/

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Afghan official: 12 killed by suicide attacker

KABUL, Afghanistan (AP) ? An Afghan official says 12 people have been killed by a suicide bomber on a motorcycle in southern Afghanistan.

Daud Ahmadi, a provincial spokesman, says at least 23 others were wounded in the Wednesday afternoon blast in Kajaki district of Helmand province.

Mohammad Ismail, the deputy of the Afghan security forces coordination office in the area, says the suicide bomber blew himself at a bridge that was under construction.

Also on Wednesday, an Afghan intelligence official in Nad Ali district of Helmand province and two of his body guards were killed in an explosion.

Ahmadi says a remote-controlled bomb was detonated as the intelligence official, Wali Mohammad Khan, walked out of his house.

THIS IS A BREAKING NEWS UPDATE. Check back soon for further information. AP's earlier story is below.

KABUL, Afghanistan (AP) ? A senior Afghan official said Wednesday that NATO forces killed five civilians, including one woman and two children, during a night raid earlier this week in northeastern Afghanistan.

A NATO statement said the alliance was aware of a military operation in Chawkay district of Kunar province on Monday and was checking into the report.

Sayed Fazelullah Wahidi, governor of Kunar province, which includes the district, said the raid occurred Monday night. He said coalition helicopters fired into a compound, killing two militants and five civilians, including a woman and two children.

Coalition troops and Afghan special forces have been carrying out regular nighttime kill-and-capture raids against suspected insurgents across Afghanistan.

But the operations and allegations of civilian deaths have provoked anger over foreign meddling in Afghanistan and whether detention operations will be run by the Afghans or Americans.

President Hamid Karzai has demanded that foreign troops stop entering homes, saying Afghan citizens cannot feel secure if they think armed soldiers might burst into their houses in the middle of the night.

In November, Karzai convened a traditional national assembly known as a Loya Jirga that stopped short of demanding a complete end to night raids. Instead, it asked that they be led and controlled by Afghan security forces.

Meanwhile, Afghan security forces said they had killed nine armed insurgents and captured 23 suspects in a series of raids in the past 24 hours.

An Interior Ministry statement issued Wednesday morning said the operations in eight different provinces also uncovered caches of weapons, ammunition and explosives.

The Afghan Defense Ministry says a soldier was killed and four were wounded in clashes with insurgents on Tuesday.

Fighting across the country appears to have decreased in recent weeks, after heavy snows blanketed much of the mountainous terrain in which the Taliban usually operate.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-01-18-AS-Afghanistan/id-ead0339db99a44eb8adc9327e609e380

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Thursday, January 19, 2012

New model for possible malaria vaccination suggests mass vaccination for low transmission areas

New model for possible malaria vaccination suggests mass vaccination for low transmission areas [ Back to EurekAlert! ] Public release date: 17-Jan-2012
[ | E-mail | Share Share ]

Contact: Clare Weaver
press@plos.org
44-122-344-2834
Public Library of Science

In the event that a vaccine for the prevention of malaria is licensed and ready for use (such as the research malaria vaccine RTS,S, which currently looks promising), distributing and giving the vaccine to three-month old infants via the World Health Organization's Expanded Programme on Immunization (EPI) will be the most efficient mechanism in high transmission areas but for lower transmission areas, mass vaccination every 5 years might be a more efficient vaccination strategy, a new study has found.

In a modelling study led by Thomas Smith from the Public Health Institute in Basel, Switzerland, and published in this week's PLoS Medicine, the authors used 14 different models that simulated the transmission of the parasite that causes malaria (P. falciparum) in thousands of hypothetical individuals through different stages of malaria infection. The authors used each model to predict the health benefits over 14 years of the potential malaria vaccine RTS,S given by different vaccination strategies and found that the predicted benefits of giving the malaria vaccine using the EPI strategy were modest and similar over a wide-range of settings. However, EPI with an initial catch-up phase averted the most deaths per vaccine dose in individuals who had over 10 infectious malaria bites a year but in areas where people typically have two or less infectious mosquito bites a year, the authors' model found that mass vaccination strategies substantially reduced transmission leading to much greater health effects per dose than other strategies, even at modest coverage.

This study only reports the first stages of using ensemble modelling to predict the health effects of RTS,S vaccination, so future studies will need to combine the outputs of multiple models with economic analyses to provide a rational basis for the design of vaccine-containing malaria control and elimination programs.

The authors say: "The ensemble modeling approach provides more robust outcomes than single models, and our analyses suggest that such an approach produces greater confidence in predictions of health effects for lower malaria transmission settings than for higher ones."

The authors continue: "This study suggests that targeted mass vaccination with RTS,S in low transmission settings may be more efficient than national-level introduction via EPI programs, but there remains a need to analyze the feasibility and economics of such strategies and the circumstances in which vaccination will avert epidemics."

###

Funding: This research was supported by the Bill & Melinda Gates Foundation grant 39777.01 and by the Malaria Vaccine Initiative. No funding bodies had any role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: Thomas A. Smith is on the Editorial Board of PLoS Medicine. AB used to be employed by the PATH Malaria Organization which was supporting the development of RTS,S, the vaccine which is the focus of this paper. AB left PATH prior to any collaboration on this paper. All other authors have declared no competing interests. The views expressed are those of the authors.

Citation: Smith T, Ross A, Maire N, Chitnis N, Studer A, et al. (2012) Ensemble Modeling of the Likely Public Health Impact of a Pre-Erythrocytic Malaria Vaccine. PLoS Med 9(1): e1001157. doi:10.1371/journal.pmed.1001157

CONTACT:

Thomas Smith

Swiss Tropical & Public Health Institute
Socinstrasse 57
Basel, CH 4002
Switzerland
+41 (0) 61-284 8273
thomas-a.smith@unibas.ch


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


New model for possible malaria vaccination suggests mass vaccination for low transmission areas [ Back to EurekAlert! ] Public release date: 17-Jan-2012
[ | E-mail | Share Share ]

Contact: Clare Weaver
press@plos.org
44-122-344-2834
Public Library of Science

In the event that a vaccine for the prevention of malaria is licensed and ready for use (such as the research malaria vaccine RTS,S, which currently looks promising), distributing and giving the vaccine to three-month old infants via the World Health Organization's Expanded Programme on Immunization (EPI) will be the most efficient mechanism in high transmission areas but for lower transmission areas, mass vaccination every 5 years might be a more efficient vaccination strategy, a new study has found.

In a modelling study led by Thomas Smith from the Public Health Institute in Basel, Switzerland, and published in this week's PLoS Medicine, the authors used 14 different models that simulated the transmission of the parasite that causes malaria (P. falciparum) in thousands of hypothetical individuals through different stages of malaria infection. The authors used each model to predict the health benefits over 14 years of the potential malaria vaccine RTS,S given by different vaccination strategies and found that the predicted benefits of giving the malaria vaccine using the EPI strategy were modest and similar over a wide-range of settings. However, EPI with an initial catch-up phase averted the most deaths per vaccine dose in individuals who had over 10 infectious malaria bites a year but in areas where people typically have two or less infectious mosquito bites a year, the authors' model found that mass vaccination strategies substantially reduced transmission leading to much greater health effects per dose than other strategies, even at modest coverage.

This study only reports the first stages of using ensemble modelling to predict the health effects of RTS,S vaccination, so future studies will need to combine the outputs of multiple models with economic analyses to provide a rational basis for the design of vaccine-containing malaria control and elimination programs.

The authors say: "The ensemble modeling approach provides more robust outcomes than single models, and our analyses suggest that such an approach produces greater confidence in predictions of health effects for lower malaria transmission settings than for higher ones."

The authors continue: "This study suggests that targeted mass vaccination with RTS,S in low transmission settings may be more efficient than national-level introduction via EPI programs, but there remains a need to analyze the feasibility and economics of such strategies and the circumstances in which vaccination will avert epidemics."

###

Funding: This research was supported by the Bill & Melinda Gates Foundation grant 39777.01 and by the Malaria Vaccine Initiative. No funding bodies had any role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: Thomas A. Smith is on the Editorial Board of PLoS Medicine. AB used to be employed by the PATH Malaria Organization which was supporting the development of RTS,S, the vaccine which is the focus of this paper. AB left PATH prior to any collaboration on this paper. All other authors have declared no competing interests. The views expressed are those of the authors.

Citation: Smith T, Ross A, Maire N, Chitnis N, Studer A, et al. (2012) Ensemble Modeling of the Likely Public Health Impact of a Pre-Erythrocytic Malaria Vaccine. PLoS Med 9(1): e1001157. doi:10.1371/journal.pmed.1001157

CONTACT:

Thomas Smith

Swiss Tropical & Public Health Institute
Socinstrasse 57
Basel, CH 4002
Switzerland
+41 (0) 61-284 8273
thomas-a.smith@unibas.ch


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-01/plos-nmf011212.php

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Russian billionaire battle reaches London court climax (Reuters)

LONDON (Reuters) ? A gargantuan lawsuit between two of post-Soviet Russia's richest and most powerful men reached its climax in a London courtroom Tuesday, with lawyers for tycoon Boris Berezovsky making their case that he was extorted into turning the crown jewel of his business empire over to billionaire rival Roman Abramovich.

The $6 billion case has thrown a spotlight on the shady business dealings of post-Soviet Russia, when opaque privatization deals turned a handful of insiders into the owners of multi-billion dollar natural resources firms.

It has also captivated the legal industry in Britain, whose globally respected, tradition-bound courts - where lawyers still wear powdered wigs - have become the venue of choice for rich Russians to sue each other, generating massive fees.

Berezovsky, 65, accuses Abramovich - known in Britain as the owner of Chelsea soccer club - of intimidating him into selling his stake in oil firm Sibneft at a knockdown price. Abramovich, 45, denies Berezovsky ever had an interest in Sibneft.

Speaking in a courtroom packed with bodyguards and ranks of lawyers and aides Tuesday, Berezovsky's lawyer devoted a large part of his closing statement to examining what he said was untruthful evidence by Abramovich and his witnesses.

"The dishonesty of Mr Abramovich and his key witnesses, their cynical manipulation of evidence and indeed of the trial process, is...perhaps the most important of the general points which my Lady will wish to have in mind when weighing up the evidence and making findings of fact in this case," Laurence Rabinowitz told judge Elizabeth Gloster.

A Kremlin insider in the 1990s under former President Boris Yeltsin, Berezovsky left Russia after falling out with Yeltsin's hand-picked successor Vladimir Putin. He says he gave up his Sibneft stake because he feared that if he refused, Abramovich would ensure Putin had the shares expropriated.

Abramovich says he paid Berezovsky $2 billion for his political patronage and protection from criminal gangs, but not as dividends from Sibneft because Berezovsky was never an owner.

Abramovich has since sold Sibneft to the Russian state natural gas monopoly Gazprom.

CLUES INTO PUTIN'S RUSSIA

The trial has been tabloid fodder in Britain ever since a tussle between the two tycoons and their retinues of bodyguards in a Hermes luxury boutique in London, when Berezovsky spotted Abramovich and served him with a writ.

During Tuesday's hearing, Berezovsky appeared relaxed, often laughing and conferring with his younger girlfriend. Abramovich, sitting at the opposite end of the courtroom, listened intently to the Russian translation of the proceedings in headphones.

The trial, which started in early October, is being followed closely by Russia watchers from London and Moscow for new clues into Russian business and politics under Putin, now prime minister but expected to become president again this year.

Abramovich and Berezovsky were close allies when making their fortunes in Russia in the 1990s under Yeltsin.

Since then, Berezovsky has become a sworn enemy of Putin, fending off requests to extradite him from London on Russian criminal charges by arguing that he could not get a fair trial in Russia. Abramovich became a Putin ally and prospered.

Britain is home to a string of high-profile Kremlin critics, one of whom, Alexander Litvinenko, was murdered in London in 2006. Moscow's refusal to extradite the man London suspects in his killing remains the largest single source of strain in Russian-British relations.

Source: http://us.rd.yahoo.com/dailynews/rss/russia/*http%3A//news.yahoo.com/s/nm/20120117/wl_nm/us_britain_russia_berezovsky

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Wednesday, January 18, 2012

John Malik: My Michelin Inspection

Greenville, SC is the North American Headquarters for Michelin. In addition to manufacturing tires, all of Michelin's travel publications are edited and published here.

July 20, 2005

In mid-July I got a phone call from a good friend of mine at the Michelin Travel Guide. Some of the Michelin Inspectors will be in town to go over the manuscript to the Red Guide to New York City and they need somewhere to have dinner. Could we accommodate a party of 14 next Wednesday? "Of course" I said "and just how many Inspectors are coming?"

"All of them" I was told.

Gulp.

The upcoming Red Guide to New York City has been perhaps one of the most talked about culinary events of recent memory. If one would believe the trade journals, these inspectors have terrorized New York for a year. The heralded chefs of New York have been lying awake at night sweating the possibility of a Michelin Star. Sous chefs have been fired, waiters berated, pots thrown and sommeliers humiliated in the quest for that star. Now they were on their way here. I hung up the phone and contemplated their visit. I had visions of the Alien Spaceship from "War of the Worlds" laying waste to civilization, panicked citizens screaming helplessly, elevated highways crumbling, entire city blocks engulfed in flame. When they were finished dining at our tiny restaurant, there would be nothing left except a smoking hole in the ground. I closed my eyes and thought about everything that could go wrong during the seven days prior to this visit. I called my wife Amy to give her the grim news. "That's so great!" she said. "They will love our place".

That night I sat down with my guys and a bottle of wine and discussed next week's menu. I threw this question out to my Sous, Tony Keely and cook Juan Muniz. "What would be the last thing that this group would expect on our menu? Something totally French that we serve and do well?"

Tony said "Pate'" and Juan said "Bouillabaisse". Now you may think that this borders on pandering. Should we style our menu just to suit our visitors? One of the great luxuries of owning a tiny, 40-seat restaurant is that we can change the menu at our discretion. Our menus have emphasized what we consider global comfort food with a touch of Southern hospitality so pate and bouillabaisse are a fine fit. After the proper amount of wine we settled on a few dishes we knew would be appropriate for mid-July: Gazpacho topped with a spicy peach sorbet, mini grilled cheddar cheese with a small bowl of warm tomato soup, smoked pork shoulder with cane vinegar, cole slaw and a buttermilk biscuit, Alaskan salmon over market succotash with lemon and chive butter, hanger steak with roasted summer vegetables and thyme oil, blueberry cobbler with our own ice cream and a roasted peach and brioche tart.

That Monday my friend at Michelin gave me a few very specific instructions concerning their upcoming meal. There were not to be any cameras in the restaurant at all. If someone were to accidentally take a photo of this group, even with a cell phone camera, the entire group would get up and leave. I was not to mention anything about the Red Guide in any way, shape or form and I was asked not to mention this to anyone in town, especially any other chefs in Greenville. "Geez" I said. "I can keep a secret, for Pete's sake!" As soon as I got off the phone I called Ben Berryhill at the Red Drum Restaurant in Mount Pleasant, about 225 miles from here.

"BEN! Guess who's eating at my place in two days?"

"Uh, the Pope?"

"No, no...the entire team of the New York City Michelin Inspectors!"

"Holy Mother of God Malik! What are you going to serve them?"

After going over the menu with Ben and getting his seal of approval it was off to the state farmer's market for some grocery shopping. Amy and I fussed over tomatoes, peaches, sweet onions, blackberries, cucumbers, tiny yellow and green squash, baby carrots, fennel, blackberries, leeks, peppers, butter beans, and corn. Shopping at the market in the summer is so pleasurable and so rewarding that I often go four or five days a week. The sweet aroma of all that great summertime produce can truly be glorious.

The next two days were spent making lobster broth and rouille for the Bouillabaisse, gazpacho, peach sorbet, blanching and peeling butterbeans, veal stock, corn stock and thyme oil. Tony got the pates made with plenty of hand-ground pork, pork fat, veal brisket and some braised rabbit. We added salt and pepper, pistachios, shallots that were roasted in duck fat, ground mustard seed and some reduced red wine then lined our terrines with bay leaf and thyme, then bacon then filled them with the pork mixture. As the pate' baked slowly in a water bath Amy made pastry cream and caramel frosting, cleaned blueberries for cobbler and roasted peaches for the tarts. Brioche dough was made the day prior then rolled into individual three-inch tart shells, proofed, baked then topped with pastry cream and half of a slow roasted peach. By Wednesday afternoon we were standing tall. I closed my eyes and thought of everything that had gone right.

When the group arrived they were all very cordial and relaxed, although I was far from it. They appeared to immediately like our tiny restaurant with its mustard colored walls, slow moving ceiling fans and smiling staff. Wine was poured, an Argyle Pinot Noir from Oregon and a French white Bordeaux, Chateau La Grande Clotte. Baskets of pomme fritte with truffle oil, parmesan and thyme are passed around and one of them mentions how enjoyable the pinot noir's of Oregon are. As our waiter Tom begins taking their order, Tony and I are trying to predict how many would order the pate' and bouillabaisse. Of the 14 dining, five go for pate and bouillabaisse. These folks are definitely homesick. The pate', gazpacho and mini-grilled cheese sandwiches with tomato soup go out and I find myself glancing over to their table every chance I get. Glasses are being raised, forks are clinking on plates, smiles and cheers all around. They love the food. More appetizers go out, three of which are the molasses brined and pecan smoked pork shoulder with the slaw and biscuit. The pork plates are getting passed around and shared and heads are nodding. The main courses are next and as I am ladling up the bouillabaisse, redolent with crayfish, mussels, shrimp, catfish, grouper and leeks I just know that they will love it. I grew up cooking gumbo in south Louisiana and I understand the importance of a dish such as Bouillabaisse. This is soul food, pure and simple. The bouillabaisse is served with plenty of our own bread and the smiles all around are genuine.

Everyone orders dessert. One gentleman asks for another smoked pork and cole slaw in lieu of something sweet. "I cannot get pork like this in France" I hear him say. He changes his mind after Tom describes Amy's brioche and roasted peach tart. As the desserts are being enjoyed I walk over and say hello. One gentleman immediately asks me if I made the brioche tart. "That was my wife," I say "and she has already left for the day."

"You will give her a big kiss for me when you get home, yes?"

"Of course" I say.

At the end of the night several of the inspectors come up to me and shake my hand, tell me thank you. They wave to Tony and Juan and smile, another mentions that our pomme fritte are better than many he has had in Paris. Yet another comes up and tells me that the local Michelin folks had spoken very highly of our restaurant and that everyone agreed that their dinner was delightful.

I call Amy and tell her how well the evening went and she chides me for all of my worrying. Alien spaceships indeed! The next day my Michelin friend calls to say how delighted they were with dinner. If we were being reviewed the consensus was that 33 Liberty would rate a Bib Gourmand, a category of unassuming, moderately priced restaurants with exceptional food. As I hang up the phone I wonder what it would have been worth to some of the New York restaurants to get a 7-day's notice of an impending Michelin inspection. Priceless, I suppose.

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Follow John Malik on Twitter: www.twitter.com/chefjohnmalik

Source: http://www.huffingtonpost.com/john-malik/my-michelin-inspection_b_1206350.html

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